Barcelona Clinic Liver Cancer staging classification and treatment schedule
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![Barcelona Clinic Liver Cancer staging classification and treatment schedule. Patients with very early hepatocellular carcinoma (HCC; stage 0) are optimal candidates for resection. Patients with early HCC (stage A) are candidates for radical therapy (resection, liver transplantation, or local ablation via percutaneous ethanol injection [PEI] or radiofrequency ablation [RFA]). Patients with intermediate HCC (stage B) benefit from transarterial chemoembolization (TACE). Patients with advanced HCC, defined as the presence of macroscopic vascular invasion, extrahepatic spread, or cancer-related symptoms (Eastern Cooperative Oncology Group performance status 1 or 2; stage C), benefit from sorafenib. Patients with end-stage disease (stage D) will receive symptomatic treatment. Treatment strategy will transition between stages based on treatment failure or contraindications for procedures. CLT=cadaveric liver transplantation; LDLT=living donor liver transplantation; M1=metastasis 1 stage; N1=node 1 stage; PST=performance status test; tx=treatment.](https://www.researchgate.net/profile/Catherine-Frenette/publication/49967533/figure/fig1/AS:601745424125968@1520478697500/Barcelona-Clinic-Liver-Cancer-staging-classification-and-treatment-schedule-Patients.png)
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