Epatocarcinoma (HCC) – Trattamento

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Addome Fegato Lesione focale Lesione maligna Oncologia Radiologia interventistica

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BCLC-2022 - BCLC 2022


Barcelona Clinic Liver Cancer staging classification and treatment schedule

Barcelona Clinic Liver Cancer staging classification and treatment schedule. Patients with very early hepatocellular carcinoma (HCC; stage 0) are optimal candidates for resection. Patients with early HCC (stage A) are candidates for radical therapy (resection, liver transplantation, or local ablation via percutaneous ethanol injection [PEI] or radiofrequency ablation [RFA]). Patients with intermediate HCC (stage B) benefit from transarterial chemoembolization (TACE). Patients with advanced HCC, defined as the presence of macroscopic vascular invasion, extrahepatic spread, or cancer-related symptoms (Eastern Cooperative Oncology Group performance status 1 or 2; stage C), benefit from sorafenib. Patients with end-stage disease (stage D) will receive symptomatic treatment. Treatment strategy will transition between stages based on treatment failure or contraindications for procedures. CLT=cadaveric liver transplantation; LDLT=living donor liver transplantation; M1=metastasis 1 stage; N1=node 1 stage; PST=performance status test; tx=treatment. 


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